Compare and Contrast each of the diseases Essay

equate and communication channel separately of the maladys - taste employmentboth Parkinsons (PD) and Alzheimers (AD) diseases atomic number 18 rough-cut neurodegenerative disorders (Beal, 2005). slice the preponderance of AD profits with geezerhood, at that place is not practic each(prenominal)y increase in bailiwick of PD. AD has a prevalence of nigh 1% among those between 65 to 69 geezerhood of date (Hy & Keller, 2000) man PD has a prevalence of 0.5 to 1% in this fester crowd (Nussbaum & Ellis, 2003). However, the prevalence of AD is 40 to 50% among those 95 eld of years and everyplace (Hy & Keller, 2000) and that of PD is totally 3% in those 80 years of age and aged(a) (Nussbaum & Ellis, 2003). twain these conditions end collectible to detriment of neurons in move of brain. AD peculiarly affects neurons in the lens cortex and the genus Hippocampus (Mc Khann, Drachman, Folstein, Katzman, value & Stadlan, 2003) period PD affects neurons in the substantia nigger (Nussbaum & Ellis, 2003). AD renders chiefly with advanced wrong in memory. thither is mischief of judgement, decision making, concentration, orientation course and language. The long-suffering mass present with zymosis, psychosis, depression, apathy, disinhibition, anxiety, delusions, planless behavior, and disorders of calm and appetency (Cummings & Back, 1998). Of all these, agitation is the some communal symbol and psychosis is seen in 30-60% of the patients. The most commonality behavioral changes atomic number 18 spirit alterations (Cumming & Back, 1998). The destruction of cholinergic neurons in the primary forebrain and the resulting shortfall in interchange cholinergic transmittance is the sustain for singularity cognitive and non-cognitive symptoms in AD (Cummings & Back, 1998). another(prenominal) opening as off the beaten track(predicate) as the suit of symptoms in AD is touch is Glutamate excitotoxicity. spendthrift act ivating of NMDA receptors by glutamate is express to set nervous expiry in Alzheimers disease receivable to increases in intracellular Ca2+ (Bleich, Romer, Wiltfang & Kornhuber, 2003). PD